Research Associate, Mass Spectrometry



Denver, CO, USA
Posted on Friday, February 2, 2024

AOA Dx is developing the next frontier in early-stage cancer detection through its pioneering work in glycolipids and proprietary biomarker technology. Our revolutionary tumor marker ganglioside platform, GlycoLocate™, is paving the way for life-saving early cancer detection. In a first of its kind, AOA Dx is developing AKRIVIS GD™, an early-stage liquid biopsy test for ovarian cancer.

We are seeking a talented and experienced Research Associate, Mass Spectrometry with a Master's degree in chemistry, biochemistry, or a related field. In this position, you will be responsible for running, troubleshooting, and performing high throughput lipidomics experiments on our state-of-the-art HPLC-MS instrument(s). This role requires a deep understanding of mass spectrometry, Thermo Scientific Mass Spectrometers, and hands-on instrumentation experience in a mass spectrometry-focused lab environment.


  • Operate, maintain and optimize HPLC-MS instruments with precision and accuracy.
  • Prepare and extract samples for analysis, ensuring high-quality results.
  • Troubleshoot instrument issues, calibrate instrumentation and perform routine maintenance.
  • Design and execute experiments involving sample analysis using mass spectrometry techniques.
  • Collaborate with cross-functional teams to provide analytical support and data interpretation.
  • Maintain accurate records of experiments and results.
  • Contribute to the development and optimization of analytical methods.
  • Stay current with emerging trends and advancements in mass spectrometry technology.


  • Master's degree in chemistry, biochemistry, or a related field.
  • Minimum of 2+ years of hands-on experience operating and maintaining an LC-MS system and running high throughput -omics experiments (lipidomics, metabolomics or proteomics)
  • Knowledge of biological sample preparation and extraction techniques for downstream LC-MS analysis
  • 5+ years' of general laboratory experience.
  • 2+ years' experience in biotech or pharma industry is preferred
  • Proficiency in HPLC-MS operation and troubleshooting.
  • Strong analytical and problem-solving skills.
  • Excellent attention to detail and ability to maintain precise records.
  • Effective communication skills and the ability to work collaboratively in a team.

The salary range for this position is $70,000 to $85,000 per year, which factors in various geographic regions. The actual compensation and seniority level for this position will be determined based on relevant experience and qualifications.

AOA Dx offers competitive benefits, including unlimited PTO, group health, dental, and vision insurance, 100% employee sponsored life and disability benefits, monthly cell phone reimbursement, and a 401k plan with employer match.

For consideration, please apply via LinkedIn or email us with your resume referencing RA MASS SPEC in the subject line to careers@aoadx.com

We foster an environment where all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation or expression, age, disability or veteran status or any other characteristics protected by law.